AListeria monocytogenesStrain Is Still Virulent despite Nonfunctional Major Virulence Genes

A Listeria monocytogenes strain is still virulent despite nonfunctional major virulence genes.

The low-virulence Listeria monocytogenes strains have been previously assigned to 4 phenotypic groups. This study aimed to characterize the A23 strain, which exhibits a pulsed-field gel electrophoresis profile specific to low-virulence strains. This strain has the same causal mutations as the group III strains and a supplementary mutation in the mpl gene, leading to the absence of internalin A ...

Phenylketonuria is still a major cause of mental retardation in Tunisia despite the possibility of treatment.

BACKGROUND AND OBJECTIVE Accumulation of phenylalanine following a deficiency of phenylalanine hydroxylase activity generates a brain damage with mental retardation: phenylketonuria (PKU). In the developing countries, where PKU systematic neonatal screening program is not established yet, the management of PKU handicap is not properly carried out. The aim of this study was to estimate the frequ...

When is a bacterial "virulence factor" really virulent?

7 Kingdom b 8 9 #Address correspondence to Elisa T. Granato, [email protected]. 13. CC-BY-NC-ND 4.0 International license not peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was. ABSTRACT 14 15 Bacterial traits that contribute to disease are termed 'virulence factors' and there is 16 much interest in therapeutic approaches th...

Lung cancer: despite advances, prevention is still best.

A Mechanism of Virulence: Virulent